upmc   PITTSBURGH CYTOGENETICS LABORATORY

 

LABORATORY SERVICES

 

FISH ANALYSIS FOR ONCOLOGIC DISORDERS

Metaphase and interphase FISH tests can be performed on cultured cells from bone marrow aspirate, oncology peripheral blood and solid tumors. Interphase FISH analysis can be carried out on paraffin embedded tissue sections, bone marrow smear and cells from body cavity fluid.

Diagnostic FISH panel or confirmatory FISH analysis will be performed with chromosome analysis on the diagnostic specimen.  The probes for follow-up FISH test will be determined based on the findings on the diagnostic specimen.  Note that, the whole FISH panel would not be repeated on remission specimens. Please see the recommended disease-specific testing algorithm.

SPECIMEN REQUIREMENTS (PDF TABLE)

ONCOLOGY STUDY REQUISITION FORM (PDF TABLE)

FISH PROBES and FISH PANELS FOR HEMATOLOGIC DISORDERS (PDF TABLE FOR PROBE LIST)

(These tables may not contain a complete list of probes available in our laboratory. Please contact the laboratory to find the availabilitiy for probles not listed in these tables.)