upmc   PITTSBURGH CYTOGENETICS LABORATORY

 

LABORATORY SERVICES

 

Chromosome Analysis on Products of Conception (poc)

Tissues from products of conception are cultured to produce metaphase cells for G-banded chromosome analysis. Analysis of 10-20 metaphases is routinely performed and additional metaphases will be studied when indicated. Two or more G-banded karyograms are created by computer image analysis on each patient.

Click to zoomINDICATIONS FOR CHROMOSOME TESTING

PREFERRED SPECIMEN TYPES

To establish cultures for karyotyping, tissues must be obtained as fresh as possible and without contamination. Carefully washing the tissue samples in sterile saline is required prior to placing them into the cell culture media or a balanced salt solution (such as Hanks) to avoid bacterial contamination. Obtaining tissue samples from more than one site can increase the yield and increase the probability of detecting mosaicism

SPECIMEN REQUIREMENTS (PDF TABLE)

CONSTITUTIONAL STUDY REQUISITION FORM (PDF TABLE)